Merck Drops One Migraine Program, Continues Another

Merck has updated the status of the clinical development programs for MK-0974 (telcagepant) and MK-3207, the company's investigational oral calcitonin gene-related peptide (CGRP) receptor antagonists for the treatment of acute migraine.

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Merck has updated the status of the clinical development programs for MK-0974 (telcagepant) and MK-3207, the company’s investigational oral calcitonin gene-related peptide (CGRP) receptor antagonists for the treatment of acute migraine. Merck is discontinuing the clinical development program for MK-3207. While efficacy was demonstrated in a Phase II study with the drug, some subjects in extended Phase I pharmacology studies were found to have experienced delayed, asymptomatic liver tes...

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